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Velkommen til vores forskningsside. Her deler vi løbende de nyeste undersøgelser og videnskabelige artikler, der understøtter vores arbejde med kræftramte børn og træning. Vores mål er at fremme forståelsen af, hvordan fysisk aktivitet kan forbedre livskvaliteten og sundheden for børn, der er ramt af kræft. Vi håber, at denne viden kan inspirere og hjælpe både fagfolk og familier


Aims: This study explores experiences of childhood cancer survivors and their parentswith a combined physical and social activity intervention during treatment, including how the survivors and their parents perceive physical activity post-treatment.

Design: A process evaluation using semi-structured interviews.

Methods: Using a criterion-sampling strategy, 18 Danish childhood cancer survivors (aged 11–18 years) and their parents were interviewed from September 2019 through May 2020. Data analysis used an inductive thematic approach focused on meaning.

Results: Three themes emerged: (1) being physically active during hospitalization; (2) peers as motivators and (3) physical activity post-treatment. During hospitalization, daily motivation to do physical activity was dependent on the daily well-being, that is, presence of the side effects from the child’s treatment. Healthy classmates provided distraction, reduced loneliness and promoted normality for those hospitalized.

For most of the survivors, their healthy peers provided motivation for being physically active during treatment. When surplus energy was lacking, some survivors preferred doing physical activity alone with a professional. Those who were physically active in the hospital sustained being physically active post-treatment while their parents continued seeking advice about appropriate activity levels.

Conclusion: Childhood cancer survivors and their parents benefited from the inter- vention which also provided guidance to remaining physically active post- treatment. This was particularly true for the participants with leukaemia.

Impact: Healthcare professionals should support children with cancer to be physically active during hospitalization. Including social and physical components in their care plan and being aware of individual preferences is pivotal to improving the survivors’ level of physical and social well-being during and post-treatment.

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Background: Children with cancer experience impaired cardiorespiratory fitness and physical function during and after treatment restricting their possibilities to engage in social activities including sport, leisure activities, and school.

The objectives were to determine the effects of classmate-supported, controlled, supervised, in-hospital, physical activity program to preserve cardiorespiratory fitness and physical function from time of diagnosis in children with cancer.

Methods: National non-randomized controlled trial including schoolchildren aged 6-18 years at diagnosis treated with chemo-/radiotherapy.

We included 120 of 128 eligible patients (94%) in the intervention group (62.5% boys, 11.2 ± 3.1 years) from East Denmark and 58 patients in the control group (57% boys, 11.0 ± 3.2 years) from West Denmark. Eight children from the control group withdrew from participation. The groups were comparable in anthropometrics and cancer diagnoses (p > 0.05). The intervention consisted of (i) supervised in-hospital physical activity from diagnosis and throughout intensive treatment, (ii) 90-min general educational session on cancer and therapy in the child’s school class, and (iii) selection of two classmates as ambassadors who took turns to support the child’s physical training during the daytime. The primary outcome was cardiorespiratory fitness (VO 2 peak, mL/ min/kg) at 6 months after diagnosis (sex, age, diagnosis adjusted).

Secondary outcomes were sit-to-stand, timed-up- and-go, handgrip strength, and balance test scores.

Results: Ambassadors were identified for all, and 2542 individual and 621 group training sessions were held. VO 2peak deteriorated over time in the control group (− 0.17 [95% CI − 0.32 to − 0.02] per week, p = 0.02), but not in the intervention group (p = 0.14). At 6 months from diagnosis, VO 2peak was higher in the intervention group
(29.6 ± 5.6 mL/kg/min) than in the control group (22.1 ± 5.6 mL/kg/min) (p = 0.01), and the intervention group had a better physical function at 3 and 6 months (p < 0.0001).

Conclusions: Peer-supported, supervised, in-hospital, physical activity is safe and feasible in children with cancer during treatment. Further, the results suggest that the intervention might mitigate impairments in cardiorespiratory fitness during treatment in children with cancer.

Trial registration: The study was prospectively registered on the 11 January 2013. NCT01772849 and NCT01772862.

Keywords: Childhood cancer, Exercise, Cardiorespiratory fitness

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